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1

Low blood concentration of hydroxychloroquine is a marker for and predictor of disease exacerbations in patients with systemic lupus erythematosus

Nathalie Costedoat-Chalumeau, Zahir Amoura, Jean-Sébastien Hulot, Hala Abou Hammoud, Guy Aymard, Patrice Cacoub, Camille Francès, Bertrand Wechsler, Du Le Thi Huong, Pascale Ghillani, Lucile Musset, P

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

2

Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography–tandem mass spectrometry

Korostelev, Marie, Bihan, Kevin, Ferreol, Lison, Tissot, Nadine, Hulot, Jean-Sebastien, Funck-Brentano, Christian, Zahr, Noël

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 898 KB

english, 2014

3

Development and Validation of a Rapid and Simple LC-MS/MS Method for Quantification of Vemurafenib in Human Plasma

Bihan, Kevin, Sauzay, Chloé, Goldwirt, Lauriane, Charbonnier-Beaupel, Fanny, Hulot, Jean-Sebastien, Funck-Brentano, Christian, Zahr, Noël

Journal:

Therapeutic Drug Monitoring

Year:

2015

Language:

english

File:

PDF, 350 KB

english, 2015

4

Emerging Drug Classes and Their Potential Use in Hypertension

Azizi, Michel, Rossignol, Patrick, Hulot, Jean-Sébastien

Journal:

Year:

2019

Language:

english

File:

PDF, 308 KB

english, 2019

5

Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: Two double-blind, randomized, placebo-controlled studies

Izzedine, Hassane, Hulot, Jean Sebastien, Launay-Vacher, Vincent, Marcellini, Patrick, Hadziyannis, Stephanos J., Currie, Graham, Brosgart, Carol L., Westland, Chris, Arterbrun, Sarah, Deray, Gilbert

Journal:

Kidney International

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

6

Genomic correction of familial cardiomyopathy in human engineered cardiac tissues

Stillitano, Francesca, Turnbull, Irene C., Karakikes, Ioannis, Nonnenmacher, Mathieu, Backeris, Peter, Hulot, Jean-Sébastien, Kranias, Evangelia G., Hajjar, Roger J., Costa, Kevin D.

Journal:

European Heart Journal

Year:

2016

Language:

english

File:

PDF, 195 KB

english, 2016

7

Association of Oral Contraceptives With Drug-Induced QT Interval Prolongation in Healthy Nonmenopausal Women

Salem, Joe-Elie, Dureau, Pauline, Bachelot, Anne, Germain, Marine, Voiriot, Pascal, Lebourgeois, Bruno, Trégouët, David-Alexandre, Hulot, Jean-Sébastien, Funck-Brentano, Christian

Journal:

JAMA Cardiology

Year:

2018

Language:

english

File:

PDF, 348 KB

english, 2018

8

Corrected QT interval in anti-SSA–positive adults with connective tissue disease: Comment on the article by Lazzerini et al

Nathalie Costedoat-Chalumeau, Zahir Amoura, Jean-Sébastien Hulot, Pascale Ghillani, Philippe Lechat, Christian Funck-Brentano, Jean-Charles Piette

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

9

Mycophenolic acid area under the curve correlates with disease activity in lupus patients treated with mycophenolate mofetil

Noël Zahr, Laurent Arnaud, Pierre Marquet, Julien Haroche, Nathalie Costedoat-Chalumeau, Jean-Sébastien Hulot, Christian Funck-Brentano, Jean-Charles Piette, Zahir Amoura

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 151 KB

english, 2010

10

Low-molecular-weight heparin vs. unfractionated heparin in percutaneous coronary intervention: A combined analysis

Maria Borentain, Gilles Montalescot, Anissa Bouzamondo, Rémi Choussat, Jean-Sébastien Hulot, Philippe Lechat

Journal:

Catheterization and Cardiovascular Interventions

Year:

2005

Language:

english

File:

PDF, 99 KB

english, 2005

11

High Doses of Clopidogrel to Overcome Genetic Resistance: The Randomized Crossover CLOVIS-2 (Clopidogrel and Response Variability Investigation Study 2)

Jean-Philippe Collet, Jean-Sébastien Hulot, Ghalia Anzaha, Ana Pena, Thomas Chastre, Claire Caron, Johanne Silvain, Guillaume Cayla, Anne Bellemain-Appaix, Jean-Baptiste Vignalou, Sophie Galier, Olivi

Journal:

Journal of the American College of Cardiology: Cardiovascular Interventions

Year:

2011

Language:

english

File:

PDF, 832 KB

english, 2011

12

Potentialisation de la fluindione et de la warfarine par la dexaméthasone dans le myélome multiple et l'amylose AL

Jérémie Sellam, Nathalie Costedoat-Chalumeau, Zahir Amoura, Guy Aymard, Sylvain Choquet, Salim Trad, Bénédicte Lebrun Vignes, Jean-Sébastien Hulot, Francis Berenbaum, Philippe Lechat, Patrice Cacoub,

Journal:

Revue du Rhumatisme

Year:

2007

Language:

french

File:

PDF, 375 KB

french, 2007

13

Planning and monitoring of placebo-controlled survival trials: comparison of the triangular test with usual interim analyses methods

Jean-Sébastien Hulot, Michel Cucherat, Andrew Charlesworth, Dirk J. Van Veldhuisen, Jean-Christophe Corvol, Alain Mallet, Jean-Pierre Boissel, John Hampton, Philippe Lechat

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 125 KB

english, 2003

14

Pharmacokinetic and pharmacodynamic interactions between metoprolol and dronedarone in extensive and poor CYP2D6 metabolizers healthy subjects

Thibaud Damy, Françoise Pousset, Henri Caplain, Jean-Sébastien Hulot, Philippe Lechat

Journal:

Fundamental & Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 444 KB

english, 2004

15

Population pharmacokinetics of tacrolimus in full liver transplant patients: modelling of the post-operative clearance

Marie Antignac, Jean Sebastien Hulot, Emmanuel Boleslawski, Laurent Hannoun, Yvan Touitou, Robert Farinotti, Philippe Lechat, Saïk Urien

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 414 KB

english, 2005

16

Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation

Larissa Lipskaia, Jean-Sébastien Hulot, Anne-Marie Lompré

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 345 KB

english, 2009

17

Thienopyridine-Associated Drug-Drug Interactions: Pharmacologic Mechanisms and Clinical Relevance

Jean-Sébastien Hulot, Jean-Philippe Collet, Gilles Montalescot

Journal:

Current Cardiology Reports

Year:

2011

Language:

english

File:

PDF, 474 KB

english, 2011

18

Quantification of coproporphyrin isomers I and III in urine by HPLC and determination of their ratio for investigations of Multidrug Resistance Protein 2 (MRP2) function in humans

Renaud Respaud, Isabelle Benz-de Bretagne, Helene Blasco, Jean Sébastien Hulot, Philippe Lechat, Chantal Le Guellec

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 556 KB

english, 2009

19

Anti-factor Xa kinetics after intravenous enoxaparin in patients undergoing percutaneous coronary intervention: a population model analysis

Paola Sanchez-Pena, Jean-Sébastien Hulot, Saïk Urien, Annick Ankri, Jean-Philippe Collet, Rémi Choussat, Philippe Lechat, Gilles Montalescot

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 406 KB

english, 2005

20

Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

Hélène Blasco, Delphine Senecal, Amélie Le Gouge, Emmanuelle Pinard, Isabelle Benz-de Bretagne, Philippe Colombat, Jean-Sébastien Hulot, Etienne Chatelut, Chantal Le Guellec

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 790 KB

english, 2010

21

Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis

Jérémie Sellam, Nathalie Costedoat-Chalumeau, Zahir Amoura, Guy Aymard, Sylvain Choquet, Salim Trad, Bénédicte Lebrun Vignes, Jean-Sébastien Hulot, Francis Berenbaum, Philippe Lechat, Patrice Cacoub,

Journal:

Joint Bone Spine

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

22

Combination of B-type natriuretic peptide and peak oxygen consumption improves risk stratification in outpatients with chronic heart failure

Richard Isnard, Françoise Pousset, Olga Chafirovskaïa, Alain Carayon, Jean Sébastien Hulot, Daniel Thomas, Michel Komajda

Journal:

American Heart Journal

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

23

Hydroxychloroquine in systemic lupus erythematosus

Nathalie Costedoat-Chalumeau, Zahir Amoura, Jean-Sébastien Hulot, Philippe Lechat, Jean-Charles Piette

Journal:

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

24

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

Jean-Philippe Collet, Jean-Sébastien Hulot, Anna Pena, Eric Villard, Jean-Baptiste Esteve, Johanne Silvain, Laurent Payot, Delphine Brugier, Guillaume Cayla, Farzin Beygui, Gilbert Bensimon, Christian

Journal:

Year:

2009

Language:

english

File:

PDF, 207 KB

english, 2009

25

Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial

Kim-Thanh Ong, Jérôme Perdu, Julie De Backer, Erwan Bozec, Patrick Collignon, Joseph Emmerich, Anne-Laure Fauret, Jean-Noël Fiessinger, Dominique P Germain, Gabriella Georgesco, Jean-Sebastien Hulot,

Journal:

Year:

2010

Language:

english

File:

PDF, 268 KB

english, 2010

26

Genetic substudy of the PLATO trial

Jean-Sébastien Hulot, Jean-Philippe Collet, Gilles Montalescot

Journal:

Year:

2011

Language:

english

File:

PDF, 116 KB

english, 2011

27

Cardiovascular Risk in Clopidogrel-Treated Patients According to Cytochrome P450 2C19*2 Loss-of-Function Allele or Proton Pump Inhibitor Coadministration: A Systematic Meta-Analysis

Jean-Sébastien Hulot, Jean-Philippe Collet, Johanne Silvain, Ana Pena, Anne Bellemain-Appaix, Olivier Barthélémy, Guillaume Cayla, Farzin Beygui, Gilles Montalescot

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

28

Antiplatelet Therapy and Coronary Artery Bypass Graft Surgery: A Fallow Land

Gilles Montalescot, Jean-Sébastien Hulot, Jean-Philippe Collet

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

29

TCT-748 Double The Dose Of Clopidogrel Or Switch To Prasugrel To Antagonize Proton Pump Inhibitor Interaction

jean-philippe collet, Jean-Sebastien Hulot, Jeremie Abtan, Ghalia Anzaha, Johanne Silvain, Matheieu Kerneis, Guillaume Cayla, Sophie Galier, Olivier Barthelemy, Farzin Beygui, Vanessa Gallois, Delphin

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 74 KB

english, 2012

30

021 2C19*2 genetic variant: a new risk factor for stent thrombosis, myocardial infarction and cardiovascular mortality

Jean-Philippe Collet, Ean-Sébastien Hulot, Jean-Baptiste Esteve, Johanne Silvain, Ana Pena, Anne Bellemain, Olivier Barthelemy, Farzin Beygui, Gilles Montalescot

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2010

Language:

english

File:

PDF, 101 KB

english, 2010

31

034 High doses of clopidogrel to overcome genetic resistance: the randomized cross-over CLOVIS-2 study

Collet, Jean-Philippe, Hulot, Jean-Sébastien, Anzaha, Ghalia, Pena, Ana, Chastre, Thomas, Silvain, Johanne, Cayla, Guillaume, Bellemain, Anne, Barthelemy, Olivier, Beygui, Farzin, Montalescot, Gilles

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2012

Language:

english

File:

PDF, 140 KB

english, 2012

32

060 Platelet reactivity and outcome in high-risk ACS patients treated with prasugrel

Cayla, Guillaume, Cuisset, Thomas, Silvain, Johanne, Hulot, Jean-Sébastien, Kerneis, Mathieu, Quilici, Jacques, O’ Connor, Stephen, Beygui, Farzin, Barthelemy, Olivier, Bonnet, Jean-Louis, Alessi, Mar

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2012

Language:

english

File:

PDF, 64 KB

english, 2012

33

016 High-on thienopyridine platelet reactivity in elderly coronary patients

Silvain, Johanne, Cayla, Guillaume, Kerneis, Mathieu, Finzi, Jonathan, Hulot, Jean-Sébastien, Bellemain-Appaix, Anne, Barthelemy, Olivier, A. O’Connor, Stephen, Collet, Jean-Philippe, Montalescot, Gil

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2012

Language:

english

File:

PDF, 103 KB

english, 2012

34

032 Clinical, angiographic and genetic determinants of early coronary stent thrombosis: The ONASSIST study

Cayla [Orateur], Guillaume, Hulot, Ean-Sébastien, O’Connor, Stephen, Silvain, Johanne, Beygui, Farzin, Barthelemy, Olivier, Gruel, Yves, Pathak, Athul, Collet, Jean-Philippe, Montalescot, Gilles

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2012

Language:

english

File:

PDF, 64 KB

english, 2012

35

067 CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics and clinical efficacy in post-myocardial infarction patients

Collet, Jean-Philippe, Hulot, Jean-Sébastien, Cayla, Guillaume, Silvain, Johanne, Bellemain, Anne, Beygui, Farzin, Barthelemy, Olivier, Allanic, Frédérick, Montalescot, Gilles

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2012

Language:

english

File:

PDF, 66 KB

english, 2012

36

Pharmacokinetic Study of Mycophenolate Mofetil in Patients with Systemic Lupus Erythematosus and Design of Bayesian Estimator Using Limited Sampling Strategies

Dr Noël Zahr, Zahir Amoura, Jean Debord, Jean-Sébastien Hulot, Franck Saint-Marcoux, Pierre Marquet, Jean Charles Piette, Philippe Lechat

Journal:

Clinical Pharmacokinetics

Year:

2008

Language:

english

File:

PDF, 147 KB

english, 2008

37

Preclinical animal models for testing iPSC/ESC-based heart therapy

Stillitano, Francesca, Karakikes, Ioannis, Costa, Kevin D., Fish, Kenneth, Hajjar, Roger J., Hulot, Jean-Sébastien

Journal:

Drug Discovery Today: Disease Models

Year:

2012

Language:

english

File:

PDF, 826 KB

english, 2012

38

An Allele-Specific PCR System for Rapid Detection and Discrimination of the CYP2C19∗4A, ∗4B, and ∗17 Alleles

Scott, Stuart A., Tan, Qian, Baber, Usman, Yang, Yao, Martis, Suparna, Bander, Jeffrey, Kornreich, Ruth, Hulot, Jean-Sébastien, Desnick, Robert J.

Journal:

The Journal of Molecular Diagnostics

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

39

Antiplatelet drug interactions with proton pump inhibitors

Scott, Stuart A, Owusu Obeng, Aniwaa, Hulot, Jean-Sébastien

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

40

Modeling CVD in Human Pluripotent Cells by Genome Editing∗

Hajjar, Roger J., Hulot, Jean-Sebastien

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 393 KB

english, 2014

41

Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance

Benz-de Bretagne, Isabelle, Zahr, Noël, Le Gouge, Amélie, Hulot, Jean-Sébastien, Houillier, Caroline, Hoang-Xuan, Khe, Gyan, Emmanuel, Lissandre, Séverine, Choquet, Sylvain, Le Guellec, Chantal

Journal:

British Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

42

Prasugrel but not high dose clopidogrel overcomes the lansoprazole neutralizing effect of P2Y12inhibition: Results of the randomized DOSAPI study

Jean-Philippe Collet,Jean-Sébastien Hulot…

Journal:

European Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 402 KB

english, 2014

43

Pharmacology and mechanisms of action of new oral anticoagulants

Salem, Joe-Elie, Sabouret, Pierre, Funck-Brentano, Christian, Hulot, Jean-Sebastien

Journal:

Fundamental & Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 214 KB

english, 2015

44

Association between ABCC2 Gene Haplotypes and Tenofovir‐Induced Proximal Tubulopathy

Izzedine, Hassane, Hulot, Jean‐Sebastien, Villard, Eric, Goyenvalle, Catherine, Dominguez, Stephanie, Ghosn, Jade, Valantin, Marc Antoine, Lechat, Philippe, Deray, and Gilbert

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 706 KB

english, 2006

45

Pharmacogenomics and personalized medicine: lost in translation?

Jean-Sébastien Hulot

Journal:

Genome Medicine

Year:

2010

Language:

english

File:

PDF, 275 KB

english, 2010

46

Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes

Jean-Sébastien Hulot,Francesca Stillitano,Joe Elie Salem…

Journal:

Stem Cell Research & Therapy

Year:

2014

Language:

english

File:

PDF, 225 KB

english, 2014

47

0466: Point-of-care genetic profiling in acute coronary syndrome

Collet, Jean-Philippe, Kerneis, Mathieu, O’Connor, Stephen, Hulot, Jean-Sébastien, Silvain, Johanne, Mansencal, Nicolas, Barthelemy, Olivier, Payot, Laurent, Brugier, Delphine, Rousseau, Héléne, Vicau

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2015

Language:

english

File:

PDF, 57 KB

english, 2015

48

Impact of Inodilator Drugs on Echocardiographic Assessments of Left Ventricular Filling Pressure in Patients With Decompensated End-Stage Heart Failure*

Salem, Joe-Elie, Aissaoui, Nadia, Paluszkiewicz, Lech, Morshuis, Michiel, Gummert, Jan, Leprince, Pascal, Fagon, Jean-Yves, Hulot, Jean Sébastien, Diebold, Benoit

Journal:

Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 615 KB

english, 2014

49

Reply to Ray and Cihlar

Izzedine, Hassane, Hulot, Jean Sebastien, Villard, Eric, Lechat, Philippe, Deray, Gilbert

Journal:

The Journal of Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 59 KB

english, 2007

50

Clinical, Angiographic, and Genetic Factors Associated With Early Coronary Stent Thrombosis

Cayla, Guillaume, Hulot, Jean-Sébastien, O’Connor, Stephen A., Pathak, Atul, Scott, Stuart A., Gruel, Yves, Silvain, Johanne, Vignalou, Jean-Baptiste, Huerre, Yves, de la Briolle, Axel, Allanic, Frédé

Journal:

JAMA The Journal of the American Medical Association

Year:

2011

Language:

english

File:

PDF, 326 KB

english, 2011